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The games I had the best time with were Anarchy Online (the twinking system), Guild Wars 1 (creating a full 6-man PvP loadout) and Path of Exile (that passive tree, even if not a MMO). I quit MMOs when everything that came out had a limited selection of very obvious skill/gear choices that a muppet could figure out and the only challenge came from the grind alone.
I am looking for something where there isn't one clear obvious way to build the most efficient character. If not a new game where things have yet to be figured out, then games with smaller populations I find usually shine where an ultimate build isn't a google search away. Sci-Fi or a darker world would be icing on the cake, but I happy just to have complex systems to dig my teeth into.
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I think the answer here would be EvE online. Not only you won't have obvious ways to build the most efficient or best loadouts (builds), but actually there aren't best loadouts as the game is highly situational and nothing is set in stone.
You can have a glimpse of what I'm talking about here: http://eve.battleclinic.com/browse_loadouts.php
Hmmmm ... the crafting system in Ryzom is something you can really dig your teeth into. And you could dig your pick very deep into the season, weather and day-cycle related forage system. Most good gear is made by player and your gear stats depend on the combination of material stats used for the crafted item. With hundreds of material combinations possible. No rng there but thinking.
Skill system is classless with lots of different combat, magic, heal, crafting and foraging skills to train. Be aware that the game can be grindy and its complexity unveals gradually, while mastering higher skill levels.
A lot of 'easy to learn but hard to master' stuff.
Game is an older sandbox, not much quests after tutorial island, so one needs to define own goals. It's an unsual fantasy setting with a kind of sci-fi background story, artful graphics but not sweetish. Community is communicative and helpful.
You can take a look at "Eldevin"
EVE online sounds perfect for you if you love theory crafting. It'll keep you very busy, and you'll have plenty of competition with other pretty intelligent theory crafters.
There is also GW2 but to a lesser extent then GW1 and really only in the structured PvP realm, but coming up with pvp builds can be pretty fun, just not as many choices as with GW1.
How about The Secret World?
My SWTOR referral link for those wanting to give the game a try. (Newbies get a welcome package while returning players get a few account upgrades to help with their preferred status.)
https://www.ashesofcreation.com/ref/Callaron/
RIP Ribbitribbitt you are missed, kid.
Currently Playing EVE, ESO
Every gun that is made, every warship launched, every rocket fired signifies, in the final sense, a theft from those who hunger and are not fed, those who are cold and not clothed.
Dwight D Eisenhower
My optimism wears heavy boots and is loud.
Henry Rollins
People have to seriously get of the god damned EVE bandwagon on this site. That game is pure crap unless you were there from day 1 or has some masochistic streak.
As for the OP, it's a dead end. Either the game becomes popular and all the answers for in-game builds are a Google search away. Or the game matures and all the classes, skills and choices homogenize into the same cookie cutters (see Darkfall for example).
EVE is best.
However, in case you want something different I suggest dual-boxing in Wizard 101. Character building itself is simplistic, but the combat is turn-based, and card-game like where you draw cards from deck then can choose one each turn to use. Every battle and every turn you'll have different cards, different spells failing, and need to re-calculate what you do. If you like theorycrafting you might like a game that forces you to theorycraft in mid-fight.
If you test dual-boxing Wizard 101 suggest a duo of storm wizard and something else, and building the characters so that they'll be able to give Storm wizard max. buffs for one single AoE spell to wipe out a group of enemies. Game before you start getting buffs that affect other spells is a bit boring, but after you get those buffs it starts getting fun.
EVE is the best game for you, I'm just trying to give other suggestions.