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I think we've all been there. You're staring down a boss when all of a sudden he/she whips out THAT spell. Yes, THAT one. Now, the word "that" could be replaced by pretty much any spell depending on who you're talking to, but today I'm listing the top 5 spells that I personally dread seeing. Here we go!
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EQ1, EQ2, SWG, SWTOR, GW, GW2 CoH, CoV, FFXI, WoW, CO, War,TSW and a slew of free trials and beta tests
Beguile use to be waaaaaay worse, it use to beguile for 3 rounds :P
For spells that deal a lot of damage to you you can either use debuffs to mitigate it, or try to have enough healing. For spells that heal your opponent a lot you can either use debuffs, or try to stun the healer, or try to make large enough damage spike that your opponent can't react.
There's not any single miracle solution, you and your team just need to play well enough.
EDIT: There is some gear with resistance, but those aren't really a solution in Wizard 101. You can edit your deck before a strong opponent if you know it's going to need specific spells.